Yep, we went there. Drinking coffee typically makes you have to go to the bathroom because of its laxative effect. But how? In some studies, researchers have found coffee might stimulate the distal colon, which pushes waste out of your body quicker, and a 1990 study in the journal Gut found it only takes four minutes for coffee to start having an effect on your bathroom schedule.
Other studies have tried to pinpoint exactly what in caffeine is helping to halt the onset of these diseases. A 2014 study (14) found that caffeine blocks various tau receptors (a protein that contributes to brain cell degeneration). Another study found that caffeinated coffee increased GCSF (15) - a substance greatly decreased in Alzheimer’s patients - levels in the bloodstream.