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If you are already a coffee drinker, it should be reassuring that after decades of research, no strong link can be found between coffee intake and cancer and, to the contrary, a number of health benefits seem to accompany coffee consumption. But, I’m not sure the evidence is powerful enough to recommend an increase in your daily habit. One reason is that we don’t know for sure that coffee consumption actually caused the health benefits observed in these studies. Some other, unmeasured factor could be responsible. Another reason is that the overall effect was small. And, it’s worth noting that some people are quite sensitive to the side effects of coffee. 

5-HIA, an organic acid and component of the neurotransmitter serotonin (the happy chemical) seen in the urine tends to be elevated in coffee drinkers, which means they may be at risk for lower levels of serotonin synthesis in the brain. Serotonin is necessary for normal sleep, bowel function, mood, and energy levels. It is a vicious cycle, as caffeine can disrupt sleep and promote anxiety and depression. We all know someone who tends to be tired, wired and over-caffeinated!
One UCLA study even famously reversed some symptoms of Alzheimer’s. What was the methodology used? A Paleo diet and lifestyle! Since a typical Paleo diet includes coconut oil, it is wise to add a little bit of this fat to your morning coffee. I personally love the taste of coconut oil in coffee, even though I am typically not a coffee drinker. Yum!
"Caffeine for treatment of Parkinson disease" Ronald B. Postuma, MD, MSc, Anthony E. Lang, MD, Renato P. Munhoz, MD, Katia Charland, PhD, Amelie Pelletier, PhD, Mariana Moscovich, MD, Luciane Filla, MD, Debora Zanatta, RPh, Silvia Rios Romenets, MD, Robert Altman, MD, Rosa Chuang, MD and Binit Shah, MD. doi:10.1212/WNL.0b013e318263570d August 1, 2012. Abstract. Accessed 15 December 2013.
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It’s enough to make a tea drinker buy an espresso machine. In a new study scientists in Germany report they were able to modify a common age-related defect in the hearts of mice with doses of caffeine equivalent to four to five cups of coffee a day for a human. The paper—the latest addition to a growing body of research that supports the health benefits of drinking coffee—describes how the molecular action of caffeine appears to enhance the function of heart cells and protect them from damage.
Unfortunately, there’s no cure for Alzheimer’s, the disorder that slowly causes memory loss and mental decline. But coffee could help reduce the risk of developing it in the first place. A 2016 meta-analysis published in the journal Nutrition found drinking high levels of coffee was associated with a reduced risk of a 27 percent reduced risk of the disease.
If you think your morning cup of joe provides nothing more to your body than a jolt of caffeine, you might be pleasantly surprised to learn that your daily cup (or three) provides some health benefits as well. Drinking moderate amounts of coffee (including decaf) has been linked to lower risk of cardiovascular disease, Type 2 diabetes, Parkinson's disease and some cancers.

The study builds on earlier work in which the two scientists showed caffeine ramps up the functional capacity of the cells that line blood vessels. The drug does so by getting into cells and stoking the mitochondria, structures within the cells that burn oxygen as they turn glucose into energy.“Mitochondria are the powerhouses of the cells,” Haendeler says. One of the things they run on is a protein known as p27. As Haendeler and Altschmied discovered (and describe in the current paper), caffeine works its magic in the major types of heart cells by increasing the amount of p27 in their mitochondria.  
If you are already a coffee drinker, it should be reassuring that after decades of research, no strong link can be found between coffee intake and cancer and, to the contrary, a number of health benefits seem to accompany coffee consumption. But, I’m not sure the evidence is powerful enough to recommend an increase in your daily habit. One reason is that we don’t know for sure that coffee consumption actually caused the health benefits observed in these studies. Some other, unmeasured factor could be responsible. Another reason is that the overall effect was small. And, it’s worth noting that some people are quite sensitive to the side effects of coffee.
How it works: There are several theories about how coffee may help prevent or protect against cognitive decline. One working theory: caffeine prevents the buildup of beta-amyloid plaque that may contribute to the onset and progression of Alzheimer’s. Researchers also theorize that because coffee drinking may be associated with a decreased risk of type 2 diabetes, a risk factor for dementia, it also lowers the risk for developing dementia.
I also tried his Bulletproof Coffee which is much smoother than regular coffee and which he claims is produced carefully to avoid the presence of mycotoxins: “Most coffee beans are processed by either leaving them in the sun and elements to wither and dry, or by pressing them and letting them ferment (spoil) to remove the outer layer of the bean. Both of these techniques are known to produce significant levels of mycotoxins as they enhance flavor. Upgraded coffee beans are mechanically processed right after picking using only clean cold water. This more expensive process is safer because it dramatically reduces harmful molds or bacteria from impacting your health.”
"Caffeine for treatment of Parkinson disease" Ronald B. Postuma, MD, MSc, Anthony E. Lang, MD, Renato P. Munhoz, MD, Katia Charland, PhD, Amelie Pelletier, PhD, Mariana Moscovich, MD, Luciane Filla, MD, Debora Zanatta, RPh, Silvia Rios Romenets, MD, Robert Altman, MD, Rosa Chuang, MD and Binit Shah, MD. doi:10.1212/WNL.0b013e318263570d August 1, 2012. Abstract. Accessed 15 December 2013.
In the 1980s and 1990s several prospective cohort studies were done to investigate the correlation between coffee and diabetes. Many of those studies reported that there is an inverse dose-dependent association with the risk of Type 2 diabetes. This means that for reasons still unclear, all those research studies found that the more coffee people with normal blood sugar drank, the less risk appeared for developing Type 2 diabetes. Several constituents in coffee might be responsible for these consistent findings.
When the morning rush gets between us and breakfast, we become our worst selves (hangry, stuck in rush-hour traffic, staring at a giant billboard of a breakfast sandwich). But here’s a way to grab breakfast and coffee on your way out the door: Brew some caffeine-packed oats in your thermos for a delicious morning meal. Not only are you getting your energizing fix, but you're also eating a solid breakfast because oatmeal comes packed with fiber and minerals like magnesium, zinc, manganese, selenium, and iron.
What I do instead is use either a very small touch of organic maple syrup or a half packet of natural stevia to just lightly sweeten my coffee.  I've also become a big fan of coconut sugar recently, and this is healthier than plain sugar because it does contain some minerals and other nutrients, and has a lower glycemic index than regular sugar.   On the other hand, if you like your coffee black with no sweetener at all, that's the healthiest way.
Katie Wells, CTNC, MCHC, Founder and CEO of Wellness Mama, has a background in research, journalism, and nutrition. As a mom of six, she turned to research and took health into her own hands to find answers to her health problems. WellnessMama.com is the culmination of her thousands of hours of research and all posts are medically reviewed and verified by the Wellness Mama research team. Katie is also the author of the bestselling books The Wellness Mama Cookbook and The Wellness Mama 5-Step Lifestyle Detox.
Do you drink your coffee first thing in the morning? You may want to think again.”Caffeine causes sugar to release into the bloodstream, creating a spike in insulin and a resulting drop in blood sugar,” says health coach and nutritionist Kristie Santana. “This will cause your body to require even more sugar, which will lead to food cravings.” Additionally, studies have found that drinking coffee first thing in the morning interferes with our bodies’ production of cortisol, which can increase your tolerance to caffeine and make you more reliant on the drink. 
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